TPM3 antibody

Catalog No. ABIN7120324

This Rabbit Polyclonal antibody specifically detects TPM3 in WB, IHC and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for TPM3 antibody (ABIN7120324)

Target: TPM3 (Tropomyosin 3 (TPM3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPM3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-TPM3 Antibody

Purpose: TPM3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: tropomyosin 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TPM3

Target: TPM3 (Tropomyosin 3 (TPM3))

Alternative Name: TPM3

Background:

Synonyms: Tropomyosin alpha-3 chain|Gamma-tropomyosin|Tropomyosin-3|Tropomyosin-5 (hTM5)|TPM3

Background: This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.

Molecular Weight: 37 kDa

Gene ID: 7170

UniProt: P06753